Anti-TNFSF11 Antibody

This rabbit polyclonal antibody from Antibodies.com targets TNFSF11 (also known as RANKL, Receptor Activator of Nuclear Factor Kappa-B Ligand), a Type II transmembrane protein of the TNF superfamily that drives osteoclast differentiation, dendritic cell maturation, and T-cell interactions. The unconjugated IgG reagent is validated for Western blot, immunohistochemistry, and immunofluorescence workflows and cross-reacts with Human, Mouse, and Rat samples, supporting comparative studies across species in bone metabolism, immunology, and oncology research. Supplied as 100 µl of liquid, the antibody can be paired with fluorescent or enzymatic secondary reagents for multiplex detection of RANKL expression in tissue sections and cell lysates. Researchers studying osteoporosis, rheumatoid arthritis, bone metastatic cancer, and inflammatory bone loss frequently use anti-TNFSF11 antibodies to examine signaling pathways linked to osteoclastogenesis and immune cell communication.