Anti-TNFRSF4 Antibody

Rabbit polyclonal antibody specific for TNFRSF4, a TNF receptor superfamily member also known as OX40 and CD134 that acts as a costimulatory molecule on activated CD4+ and CD8+ T lymphocytes. The ligand partner OX40L (TNFSF4) engages this receptor to promote T cell survival, clonal expansion, and memory formation, which is why TNFRSF4 is a frequent subject of cancer immunotherapy and autoimmune disease research, including studies of multiple sclerosis, systemic lupus erythematosus, and inflammatory bowel disease. Provided unconjugated at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.3, this Antibodies.com reagent is validated for western blot and cross-reacts with human, mouse, and rat samples, supporting comparative work across model organisms. The 100 µl pack size supplies ample volume for multiple blotting experiments probing this activation-induced receptor of the TNFR superfamily.