Anti-TNFRSF1B Antibody

This polyclonal reagent from Antibodies.com targets TNFRSF1B (also referred to as TNFR2 or p75), an approximately 75 kDa transmembrane receptor that binds TNF-alpha and recruits TRAF2 to drive NF-κB signaling in immune and stromal cells. The antibody was raised in rabbit and is supplied as an unconjugated preparation at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, with a total volume of 100 µl.

The reagent is validated for western blot (WB) and immunohistochemistry (IHC) on human samples, where it supports detection of full-length and shed TNFR2 species in tissue lysates and formalin-fixed paraffin-embedded sections. Laboratories studying regulatory T-cell biology, chronic inflammatory disease, or tumor microenvironment frequently use this reagent to compare receptor expression across immune subsets.

Storage at -20 °C in the supplied glycerol buffer is recommended, with protection from light and avoidance of repeated freeze-thaw cycles to preserve antibody activity across downstream applications.