Anti-TNFRSF10D Antibody

The Anti-TNFRSF10D polyclonal antibody from Antibodies.com is a rabbit-host IgG reagent raised against human TNFRSF10D, also known as TRAIL-R4 or DcR2, a member of the TNF receptor superfamily that acts as a decoy receptor for TRAIL. The unconjugated preparation is supplied as 100 µl of liquid and is validated for Western blot and flow cytometry, supporting detection of endogenous receptor in cell lysates and on the surface of intact cells.

TNFRSF10D lacks a functional cytoplasmic death domain, and its expression has been linked to resistance of certain tumor lines to TRAIL-mediated apoptosis. Researchers apply this reagent to investigate apoptosis regulation, map TRAIL pathway signaling, and profile receptor distribution across human cell types and tissue samples. The polyclonal format provides recognition of multiple epitopes on the target, which can be useful when monitoring changes in expression or post-translational state.

Provided as a polyclonal rabbit IgG, unconjugated and intended for Western blot and flow cytometry. Refrigerate upon receipt; for longer storage, aliquot and freeze to limit freeze-thaw cycles of the antibody preparation.