Anti-TNFRSF10B Antibody

Raised in rabbit against the human TNFRSF10B receptor, this unconjugated polyclonal reagent is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, and is calibrated for routine Western blot workflows. The antibody recognizes TNFRSF10B, the death-domain-containing TRAIL receptor also referred to as DR5, KILLER, TRICK2, or ZTNFR9, and is verified for detection in human, mouse, and rat samples.

Researchers studying extrinsic apoptosis, TRAIL signaling, and tumor cell sensitivity to death-receptor agonists use this reagent to probe receptor expression in whole-cell lysates and tissue homogenates. Provided by Antibodies.com as a 100 µl aliquot of ready-to-use liquid, this primary antibody is stored at –20 °C in its working buffer and is intended for research use only in Western blot workflows.

The polyclonal format offers epitope diversity across both the extracellular TRAIL-binding region and the intracellular death domain, supporting studies of receptor clustering, caspase-8 recruitment, and ligand-induced apoptosis in cancer cell biology, immunology, and apoptotic-signaling research.