Anti-TNF12 Antibody

TNF12 (also called TWEAK and TNFSF12) is a multifunctional cytokine of the tumor necrosis factor ligand superfamily that signals through the Fn14 receptor to regulate inflammation, cell survival, angiogenesis, and tissue remodeling. This rabbit polyclonal reagent, supplied by Antibodies.com as an unconjugated primary antibody, is raised against TNF12 and validated for western blotting (WB), immunohistochemistry (IHC), and immunofluorescence (IF) on human and mouse samples, supporting studies of immune signaling, wound repair, and tumor microenvironment biology. The 100 µl vial contains affinity-purified antiserum in a ready-to-use format that can be aliquoted to limit freeze-thaw cycles and stored at -20 degrees C to preserve long-term activity. Researchers investigating NF-κB pathway activation, cytokine crosstalk, or autoimmune disease models can apply the antibody to detect endogenous TNF12 in cultured cells, tissue sections, and lysates without secondary-conjugate interference, since the unconjugated format allows pairing with custom reporter-labeled secondary reagents. The polyclonal nature of the reagent increases the likelihood of recognizing multiple epitopes on TNF12, which is useful when probing denatured target protein on membranes or fixed specimens in situ.