Anti-TNF11 Antibody

This polyclonal antibody from Antibodies.com targets TNF11 (TNFSF11), also known as RANKL, TRANCE, or OPGL, a type II transmembrane protein of the tumor necrosis factor ligand superfamily. It regulates osteoclast formation, dendritic cell survival, and lymphocyte development through receptor activator of NF-κB (RANK) signaling. The reagent is raised in rabbit, supplied unconjugated as a 100 µl vial, and validated for Western blot and immunofluorescence workflows against human and mouse samples. Researchers apply it to osteoimmunology and bone-remodeling investigations, including studies of rheumatoid arthritis, periodontal bone loss, postmenopausal osteoporosis, osteopetrosis, and tumor-associated skeletal metastasis. The unconjugated format allows flexibility for secondary antibody pairing or custom labeling depending on experimental needs.