Anti-TNF alpha Antibody

The Antibodies.com polyclonal reagent targets tumor necrosis factor alpha, a key pro-inflammatory cytokine involved in innate immunity, septic shock response, and chronic inflammatory disease models. Produced in rabbit hosts and purified as an IgG immunoglobulin, this unconjugated preparation is validated for western blot detection of mouse TNF alpha in cell lysate and tissue homogenate samples, as well as ELISA quantification of secreted cytokine in culture supernatant. Supplied as 100 µg of liquid antibody in a single vial, the reagent should be stored refrigerated at 4 degrees C for short term use or frozen in single-use aliquots to limit freeze-thaw cycles and preserve epitope recognition. Researchers studying macrophage activation, Th1/Th2 polarization, or inflammatory bowel disease models will find this polyclonal advantageous for recognizing multiple epitopes on the TNF alpha homotrimer compared with monoclonal alternatives.