Anti-TNF-α Antibody

Raised in rabbits against human tumor necrosis factor alpha, this unconjugated polyclonal reagent from Antibodies.com is supplied as 50 µl of ready-to-use antibody for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows.

The antibody cross-reacts with mouse and rat TNF-α in addition to the human protein, supporting comparative inflammation and immunology studies across rodent model systems. Researchers commonly apply it to investigate cytokine signaling in conditions such as rheumatoid arthritis, inflammatory bowel disease, and sepsis, where TNF-α serves as a key biomarker of immune activation.

The unconjugated format allows flexible pairing with secondary antibodies or custom labeling strategies. For short-term bench use, refrigerate at 4 °C; for longer storage, aliquot and freeze to preserve antibody activity across freeze-thaw cycles.