Anti-TNAP Antibody

Recombinant rabbit monoclonal antibody from Antibodies.com, raised against Tissue-Nonspecific Alkaline Phosphatase (TNAP), the membrane-bound isozyme encoded by the ALPL gene that hydrolyzes extracellular pyrophosphate and supports skeletal mineralization. The unconjugated reagent is supplied as 100 µl of liquid in a vial, formulated in TBS (pH 7.4) with 1% BSA and 40% glycerol as cryoprotectant, and preserved with 0.05% sodium azide. For long-term stability, aliquot upon receipt and store at -20 °C, avoiding repeated freeze-thaw cycles. Validated for western blot, immunocytochemistry, immunohistochemistry, immunoprecipitation, and flow cytometry, with reactivity confirmed in human, mouse, and rat samples. The reagent suits research use only investigations of bone biology, hypophosphatasia disease models, vascular calcification, stem-cell osteogenesis, and broader alkaline phosphatase isoenzyme profiling across tissues and cell lines.