Anti-TMSB4X Antibody

The Anti-TMSB4X polyclonal antibody from Antibodies.com is a rabbit IgG reagent raised against thymosin beta-4, a small 4.9 kDa actin-sequestering peptide encoded on the X chromosome and expressed in nearly every human tissue. Supplied as 50 µl of unconjugated antiserum, it is validated for western blot and immunofluorescence workflows and cross-reacts with mouse and rat orthologs in addition to human samples, supporting comparative studies across common mammalian model systems.

TMSB4X research focuses on its central role in G-actin monomer sequestration, cytoskeletal remodeling, cell migration, angiogenesis, and tissue repair, making this reagent useful for projects in wound healing, regenerative biology, cardiac injury models, and tumor cell motility. The antibody is shipped as a liquid aliquot and should be stored at -20 °C in small working volumes to limit repeated freeze-thaw cycles that erode polyclonal IgG titer.

For western blot, expect a band near the 5 kDa region using Tricine or other high-resolution SDS-PAGE systems, because thymosin beta-4 runs anomalously small on standard Laemmli gels. The unconjugated format lets users pair it with their preferred HRP, fluorophore, or biotin secondary reagents for both chromogenic and fluorescence imaging platforms, and the cross-reactivity profile across human, mouse, and rat samples makes it a flexible choice for validation experiments in cell culture lysates and tissue sections.