Anti-TMPRSS4 Antibody

This primary polyclonal antibody from Antibodies.com targets human TMPRSS4 (transmembrane serine protease 4), a type II membrane-bound serine protease that has attracted attention in oncology research for its involvement in epithelial-mesenchymal transition, extracellular matrix remodeling, and invasive behavior of tumor cells. The reagent is raised in rabbit and supplied as 100 µl of unconjugated antiserum, allowing investigators to choose their own detection label for Western blot and immunohistochemistry workflows.

TMPRSS4 is overexpressed in several solid tumor types, including pancreatic ductal adenocarcinoma, non-small cell lung cancer, colorectal carcinoma, and gastric carcinoma, where elevated protein levels correlate with poorer clinical outcomes. Researchers use anti-TMPRSS4 reagents to characterize expression patterns in patient-derived tissue sections by IHC and to monitor protein abundance and migration behavior in cell lysates by Western blot. Human reactivity is confirmed, making the antibody appropriate for studies of cell lines and primary tissues of human origin.

Aliquot upon first use and store at -20°C in working volumes to limit freeze-thaw cycles; protect from light when using chromogenic or fluorescent detection systems. For research use only.