Anti-TMPRSS3 Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com targets the TMPRSS3 protein, a type II transmembrane serine protease best known for its role in inner-ear ion homeostasis and auditory function. The reagent is supplied as a 100 µl aliquot of polyclonal serum, validated for western blot and immunofluorescence workflows, and shows reactivity against both human and mouse TMPRSS3.

TMPRSS3 (transmembrane protease, serine 3) is expressed in the cochlea, where loss-of-function mutations have been mapped to autosomal recessive non-syndromic hearing loss, including the DFNB8 and DFNB10 loci. Researchers working on hereditary deafness, cochlear development, and auditory neuroscience use this reagent to localize TMPRSS3 in fixed tissue sections by immunofluorescence and to confirm endogenous expression in cell lysates by western blot. The antibody is provided unconjugated in a vial, raised in rabbit, and is intended for research use only.