Anti-TMEM173 Antibody

TMEM173, also known as STING (Stimulator of Interferon Genes), is a transmembrane protein localized to the endoplasmic reticulum that plays a central role in innate immune sensing of cytosolic DNA. This unconjugated rabbit polyclonal antibody from Antibodies.com was raised against TMEM173 and recognizes both human and mouse orthologs, supporting cross-species comparative studies in immunology and cell signaling research.

Validated for western blot and ELISA workflows, the reagent is supplied as 100 µl of polyclonal antiserum in a vial and is intended for research use only in laboratory settings. Investigators studying cGAS-STING pathway activation, type I interferon responses, antiviral defense mechanisms, and tumor microenvironment immunology commonly use this reagent to probe STING expression, oligomerization, and post-translational modifications in cell lysates and tissue homogenates.

Storage recommendations accompany the product; aliquoting upon receipt is advised to preserve activity across multiple freeze-thaw cycles. The unconjugated format offers flexibility for downstream labeling with HRP, biotin, or fluorophore conjugates, depending on the chosen detection strategy.