Anti-TLK1 (phospho-S743) Antibody

This rabbit polyclonal antibody from Antibodies.com specifically detects TLK1 phosphorylated at serine 743, a regulatory modification on the Tousled-like kinase 1 that rises during the DNA damage response and S-phase progression. The reagent is raised against the phospho-S743 epitope and validated for Western blot across human, mouse, and rat samples, supporting work on chromatin assembly, replication stress, and ATM/ATR checkpoint signaling.

Supplied unconjugated as 100 µl at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, the antibody drops into standard immunoblotting workflows. The polyclonal format offers broader recognition of the modified kinase than a monoclonal reagent, while the glycerol-stabilized buffer allows refrigerated storage with optional aliquoting for longer term use. Researchers studying genome stability, post-translational kinase regulation, or replication-coupled signaling will find this a focused reagent for monitoring TLK1 activation status by Western blot.