Anti-TK1 Antibody

Thymidine Kinase 1 (TK1) is a cytosolic enzyme that phosphorylates thymidine to thymidine monophosphate as part of the salvage pathway for DNA synthesis, and its expression rises sharply during S-phase, which is why it has become a long-standing marker of proliferating cells in tumor biology and cell-cycle research. The Antibodies.com rabbit polyclonal reagent against TK1 is supplied as an unconjugated, liquid preparation in a 100 µl vial, ready to pair with a user-selected secondary antibody for chromogenic or fluorescence readouts.

Validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF), the antibody recognizes the endogenous TK1 protein in human, mouse, and rat samples, which makes it practical for studies that move between rodent disease models and human tissue microarrays within a single project. It is commonly used by groups working on hepatocellular carcinoma, breast cancer, lung cancer, and hematological malignancies to score proliferative indices in tumor sections, and it is similarly useful for monitoring cell-cycle re-entry in synchronized cultures or for tracking division in developmental biology samples.

Because the reagent is unconjugated, it can be matched to HRP, biotin, or fluorescent secondaries and adapted to either DAB-based chromogenic IHC or multi-color IF panels. Keep the vial refrigerated, protect it from light, and avoid repeated freeze-thaw cycles by preparing small working aliquots. This primary antibody is intended for research use only.