Anti-TJP3 Antibody

Produced by Antibodies.com as a rabbit polyclonal reagent, this unconjugated antibody recognizes Tight Junction Protein 3 (TJP3), also known as ZO-3, a MAGUK-family scaffold protein that localizes to tight junctions in epithelial and endothelial cell layers. The antibody is supplied at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.2, and is validated for Western blot (WB) detection of the human, mouse, and rat target. Researchers use this reagent to investigate epithelial barrier assembly, paracellular permeability, cell-cell adhesion dynamics, and the localization of tight junction components such as occludin, claudins, and ZO-1 in tissue and cell line lysates. Each vial contains 100 µl of ready-to-use liquid, and the polyclonal format provides recognition of multiple epitopes on the TJP3 cytoplasmic domain, supporting consistent signal across denaturing immunoblotting workflows. Store refrigerated at 2-8 degrees C and protect from light to preserve activity, and avoid repeated freeze-thaw cycles by aliquoting on first use.