Anti-TIMP2 Antibody

Raised in rabbit against the tissue inhibitor of metalloproteinases 2 (TIMP2) target, this unconjugated polyclonal reagent from Antibodies.com is supplied as 100 µl of a 1 mg/ml solution in PBS containing 0.1% sodium azide as a preservative and 50% glycerol as a stabilizing cryoprotectant.

TIMP2 is a ~24 kDa secreted glycoprotein that endogenously regulates matrix metalloproteinase (MMP) activity and participates in cell cycle control through interaction with cyclin-dependent kinase complexes, making it a focal target for studies of extracellular matrix remodeling, tumor invasion and angiogenesis, and fibrotic disease progression.

Validated for western blot, immunohistochemistry, and immunofluorescence workflows, this primary antibody cross-reacts with human, mouse, and rat samples, supporting translational research from rodent disease models to clinical specimens. The supplied buffer formulation is suitable for refrigerated storage; aliquoting on receipt is recommended to limit freeze-thaw cycles and preserve binding activity across repeated experiments, while sodium azide handling precautions apply for downstream conjugation or live-cell applications.