Anti-TIMP-1 Antibody

Manufactured by Antibodies.com, this research-grade polyclonal reagent is raised in rabbit against tissue inhibitor of metalloproteinases 1 (TIMP-1) and is supplied as 50 µL of an affinity-purified antiserum at a working concentration of 1 mg/mL. The antibody is unconjugated and is formulated in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide; it is shipped cold at 4°C and, upon delivery, should be transferred to -20°C with repeated freeze/thaw cycles avoided. Validated applications span ELISA, Western blot, immunocytochemistry/immunofluorescence and immunohistochemistry, allowing flexible use across multiple assay formats in cell and tissue-based workflows. The immunogen corresponds to a synthetic peptide derived from the internal region of human TIMP-1, and the reagent specifically detects endogenous levels of the TIMP-1 protein in samples from human, mouse and rat origins. Purification is performed by affinity chromatography using the epitope-specific immunogen, delivering clean and specific detection performance suitable for investigations into extracellular matrix remodeling, fibrosis, inflammation and cancer-related matrix biology studies.