Anti-TICAM2 Antibody

Rabbit polyclonal antibodies from Antibodies.com are raised against TICAM2 (also known as TRAM), a TIR domain-containing adapter molecule that participates in Toll-like receptor signaling. TICAM2 serves as a bridging factor between TLR4 and TRIF, facilitating the MyD88-independent arm of innate immune activation and supporting induction of type I interferon responses. This unconjugated reagent is supplied at 50 µl per vial and is validated for Western blot detection of endogenous TICAM2 protein in human and rat samples. Produced in rabbits and of the IgG isotype, it is intended for downstream detection with standard anti-rabbit IgG secondary reagents. Researchers studying TLR4 signaling, endotoxin-activated inflammatory pathways, viral sensing, or comparative innate immunity in rodent and human systems can use this reagent to probe TICAM2 expression and subcellular localization. For storage, aliquot the antibody upon arrival and store frozen to limit freeze-thaw cycles, handling vials on ice to preserve activity. Each vial is supplied for research use only and is not intended for diagnostic or therapeutic applications.