Anti-TIA1 Antibody

Raised in rabbit, this unconjugated polyclonal reagent from Antibodies.com is specific for TIA1 (T-cell-restricted intracellular antigen-1), an RNA-binding protein that regulates alternative pre-mRNA splicing and nucleates cytoplasmic stress granules during the cellular stress response. The IgG is supplied in a 50 µL volume and cross-reacts with Human, Mouse, and Rat samples, supporting comparative work across standard mammalian model systems. Validated for Western blot and immunofluorescence, the antibody enables immunoblotting of TIA1 isoforms and imaging of stress granule assembly in cultured cells following arsenite or heat-shock induction, with downstream relevance to studies of mRNA metabolism, translational control, and apoptosis signaling.