Anti-Thrombopoietin Antibody

This rabbit polyclonal antibody from Antibodies.com targets thrombopoietin (TPO), the hepatic cytokine that drives megakaryocyte maturation and platelet production through the c-Mpl receptor. Raised in rabbit and supplied as an IgG fraction at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the reagent is validated for Western Blot detection across human, mouse, and rat samples. The unconjugated format supports flexible pairing with secondary reporters of the user's choice, including HRP- or fluorophore-labelled anti-rabbit reagents, and the polyclonal design enables recognition of multiple epitopes on the native TPO protein for robust signal in tissue and cell lysates. Each vial contains 100 µl of working stock, typically sufficient for many blotting membranes depending on dilution, and the glycerol cushion stabilises the protein during routine handling. For short-term use, refrigerate at 4 °C; for longer storage, aliquot and freeze at -20 °C, avoiding repeated freeze-thaw cycles. Common in vitro research applications include studies of bone marrow failure syndromes, idiopathic thrombocytopenia, cytokine regulation of haematopoiesis, and signalling through the JAK-STAT pathway downstream of c-Mpl, where reliable detection of endogenous TPO levels is required.