Anti-THRB Antibody

Raised in rabbit and offered through the Antibodies.com catalogue of primary antibodies, this polyclonal reagent targets the thyroid hormone receptor beta (THRB), a nuclear receptor encoded by the THRB gene (also known as c-erbA-2, ERBA2, NR1A2, and THR1). The antibody was generated against a recombinant human THRB immunogen and subsequently affinity-purified, ensuring selective recognition of endogenous total THRB protein in experimental samples. It is supplied unconjugated at a concentration of 1.0 mg/mL, prepared in a phosphate-buffered saline (pH 7.4) formulation containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol as a stabiliser. Validated applications include Western blot (WB) and immunocytochemistry/immunofluorescence (ICC/IF), making it suitable for both lysate-based expression analysis and subcellular localisation studies. The reagent cross-reacts with human, mouse, and rat samples, supporting comparative work on thyroid hormone signalling across species. Each vial contains 50 µL of the ready-to-use antibody solution; the larger 100 µL format is also available from Antibodies.com for higher-throughput needs. The product is shipped at 4 °C, and upon arrival it should be aliquoted and stored at -20 °C, with care taken to avoid repeated freeze/thaw cycles to preserve activity. Intended for research use only, this THRB polyclonal antibody from Antibodies.com provides a reliable tool for probing nuclear receptor expression in cell and tissue lysate preparations.