Anti-TH Antibody

Tyrosine hydroxylase (TH) is the rate-limiting enzyme in catecholamine biosynthesis, converting L-tyrosine to L-DOPA in dopaminergic and noradrenergic neurons. This rabbit polyclonal antibody from Antibodies.com recognizes TH and supports detection across human, mouse, and rat samples, making it a widely used marker in neuroscience and neuropathology workflows.

Provided as 100 µl of unconjugated antiserum, the reagent is validated for Western blot, immunohistochemistry, immunofluorescence, and ELISA applications. Researchers routinely apply it to map catecholaminergic pathways, characterize neuronal differentiation, and study models of Parkinson's disease, addiction, and stress response. Polyclonal reactivity against multiple epitopes on the TH protein helps generate strong signal in tissue sections and lysates prepared from brain, adrenal medulla, and peripheral sympathetic tissue.

The unconjugated format offers flexibility for downstream labeling, allowing users to pair the primary reagent with custom fluorophores, HRP, or biotin conjugates depending on the experimental design.