Anti-TGFB1 Antibody

TGFB1 (Transforming Growth Factor Beta 1) is a multifunctional cytokine central to fibrosis research, immune regulation, wound healing, and tumor biology studies. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com specifically recognizes TGFB1 and is validated for western blot and immunohistochemistry applications. The unconjugated format supports flexible pairing with user-selected secondary detection systems, including HRP, biotin, or fluorophore-conjugated anti-rabbit reagents.

The antibody cross-reacts with endogenous TGFB1 in human, mouse, and rat samples, enabling comparative studies across model organisms in tissue sections and whole-cell lysates. Common research applications include investigation of epithelial-mesenchymal transition, extracellular matrix deposition, inflammatory signaling cascades, and tumor microenvironment remodeling. The polyclonal format recognizes multiple epitopes on the TGFB1 precursor and mature peptide, which can aid detection of post-translationally processed forms of the cytokine.

Supplied as 100 µl of liquid antibody in a single vial, the reagent is sufficient for multiple immunoblotting and staining experiments when titrated appropriately. For optimal preservation, aliquot upon arrival and store at -20 degrees C, avoiding repeated freeze-thaw cycles. Standard immunohistochemistry protocols on formalin-fixed paraffin-embedded sections, as well as western blot analysis of denatured cell or tissue lysates, are supported using this antibody.