Anti-TGF beta Antibody [2C6]

Engineered for research applications, this unconjugated mouse monoclonal antibody from Antibodies.com targets human Transforming Growth Factor beta (TGF-β), a key regulator of cell proliferation, immune modulation, and extracellular matrix biology. The IgG1 clone 2C6 is supplied as a 100 µg lyophilised vial validated for Western Blotting (WB) and Immunohistochemistry (IHC) workflows on human samples.

TGF-β is a pleiotropic cytokine implicated in epithelial-mesenchymal transition, tumor microenvironment signaling, fibroblast-to-myofibroblast conversion, and chronic inflammatory responses. Investigators use this reagent to study Smad-dependent signal transduction, downstream transcriptional targets, and receptor-ligand interactions relevant to fibrosis, oncology, and regenerative medicine research. The unconjugated format permits flexible labeling with HRP, biotin, or fluorophore conjugates to match diverse detection platforms.

Reconstitute the lyophilised powder in sterile distilled water or appropriate buffer to the desired working concentration. For long-term use, aliquot the reconstituted antibody and store at low temperature, avoiding repeated freeze-thaw cycles to preserve binding activity. This reagent is intended for research use only and provides reproducible detection of human TGF-β in cell lysates, paraffin tissue sections, and conditioned culture media.