Anti-TGF alpha Antibody

This polyclonal antibody targets Transforming Growth Factor alpha (TGFα), an EGF-family ligand that signals through the EGFR pathway and drives epithelial cell proliferation, wound healing, and tumor progression. Generated in rabbit and supplied as an unconjugated 100 µl liquid, the reagent is validated for Western blot and immunohistochemistry workflows on human, mouse, and rat tissue, allowing researchers to track endogenous ligand expression in cell lysates, organoid models, and paraffin-embedded sections. Independent studies have mapped TGFα overexpression in squamous carcinomas, glioblastoma, and inflammatory skin lesions, making this reagent useful for cancer biology, dermatology, and regenerative-medicine projects that need to compare ligand levels across species. The polyclonal format increases the likelihood of recognizing multiple epitopes on the processed and membrane-bound forms of the protein, which is helpful when probing cleavage variants or fixation-masked targets in archival samples. Researchers commonly pair it with EGFR downstream readouts such as phospho-Erk and phospho-Akt to build a complete signaling picture. Antibodies.com provides the lot-specific validation data and recommended dilution ranges to support reproducible results.