Anti-TGFβ RII Antibody

Produced in rabbit as an unconjugated polyclonal reagent, this Antibodies.com primary antibody recognizes TGF-beta receptor type II, a transmembrane serine/threonine kinase central to signal transduction by the transforming growth factor-beta superfamily. The reagent is validated for Western blot, immunohistochemistry, and ELISA workflows, accommodating protein detection, tissue localization, and quantitative immunoassay readouts within a single antibody lot.

Confirmed cross-reactivity with human, mouse, and rat samples addresses translational research and comparative studies across multiple model systems. Each vial contains 100 µl of antibody, accommodating working-stock dilutions and aliquoting for long-term storage while preserving activity across repeated freeze-thaw cycles when handled appropriately.

Because the antibody is unconjugated, laboratories can pair it with HRP, biotin, or fluorophore-labeled secondary reagents to match the requirements of a chosen detection platform. Investigators studying TGF-beta signaling in fibrosis, cancer, immune regulation, and developmental biology use this reagent to examine receptor expression, ligand binding contexts, and downstream SMAD pathway activation in cell culture and tissue-derived specimens.