Anti-TGFβ3 Antibody

Supplied as 100 µl of unconjugated rabbit polyclonal antiserum raised against Transforming Growth Factor Beta 3, this Antibodies.com primary antibody detects a 25 kDa homodimeric cytokine of the TGF-β superfamily that signals through the TβRII/TβRI (ALK5) receptor complex to govern epithelial-mesenchymal transition, palatal fusion, wound repair, and fibrotic remodeling.

Validated for Western blot, immunohistochemistry, and ELISA, the reagent cross-reacts with TGFβ3 from human, mouse, rat, and monkey samples, supporting comparative work in developmental biology, regenerative medicine, and tumor microenvironment research. Because TGFβ3 is secreted as a latent precursor that requires proteolytic activation before engaging its receptors, lysate preparation should preserve both pro- and mature forms, and endogenous expression in many tissues is low, so enriched fractions or concentrated conditioned media often yield cleaner signals than whole-tissue homogenates.

The antibody is shipped in a single vial as a liquid, intended for research use only, and should be stored refrigerated with brief freeze-thaw cycles minimized to protect binding activity over its working shelf life.