Anti-TFB2M Antibody

This rabbit polyclonal reagent targets TFB2M, the mitochondrial transcription factor B2 that supports mitochondrial RNA polymerase activity in human cells. Produced by Antibodies.com as an IgG preparation in an unconjugated format, the antibody is supplied as 200 µL of liquid and is validated for Western blot and immunohistochemistry workflows. TFB2M is a nuclear-encoded factor imported into mitochondria, where it drives transcription of the mitochondrial genome and influences mitochondrial biogenesis, oxidative phosphorylation capacity, and cellular respiration. Researchers studying mitochondrial disorders, metabolic disease, neurodegeneration, and cancer metabolism use TFB2M-specific antibodies to assess protein expression across human tissue sections and cell lysates. With confirmed reactivity against human TFB2M, the reagent enables detection of the full-length protein in IHC staining of paraffin-embedded samples and in Western blot analysis of mitochondrial fractions, supporting studies of mitochondrial gene regulation.