Anti-TF2H1 Antibody

This rabbit polyclonal antibody targets TF2H1 (General Transcription Factor IIH subunit 1), a core scaffold component of the multifunctional TFIIH complex. TFIIH participates in RNA polymerase II transcription initiation and nucleotide excision repair, supporting research into DNA damage response, transcription-coupled repair, cell cycle regulation, and xeroderma pigmentosum. The unconjugated reagent is supplied by Antibodies.com at 100 µl per vial and is validated for Western blot (WB) and immunohistochemistry (IHC). Raised in rabbit as a polyclonal antibody, it shows reactivity against both human and mouse TF2H1, enabling cross-species investigation of transcription factor biology and DNA repair mechanisms. Researchers commonly apply this reagent to detect endogenous TF2H1 in cell lysates and tissue sections, pairing it with appropriate HRP- or fluorophore-conjugated secondary antibodies for chemiluminescent or immunofluorescence detection. For best results, aliquot upon arrival and store at -20°C, avoiding repeated freeze-thaw cycles to preserve antigen-binding activity.