Anti-Tetraspanin-8 Antibody

Antibodies.com offers this rabbit polyclonal reagent raised against human Tetraspanin-8 (TSPAN8), a four-transmembrane-domain cell-surface glycoprotein in the tetraspanin family. Each vial provides 100 µl of unconjugated antibody suited to western blot, immunohistochemistry, immunofluorescence, and ELISA workflows.

TSPAN8 partitions into tetraspanin-enriched microdomains on epithelial and tumor cell membranes, where it modulates cell adhesion, motility, and growth-factor receptor crosstalk. Researchers apply this reagent to studies of epithelial-mesenchymal transition, colorectal and pancreatic tumor progression, angiogenesis assays, and tissue-level expression mapping in biopsy material.

On receipt, aliquot the antibody and store at -20 °C for long-term use, avoiding repeated freeze-thaw cycles to preserve binding activity. The unconjugated format gives flexibility to conjugate the reagent to a preferred label or to use it directly in chromogenic and fluorescence detection protocols.