Anti-TET2 (di methyl R1682) Antibody

Raised in rabbit and supplied as 50 µl in a vial, this unconjugated polyclonal IgG reagent from Antibodies.com specifically recognizes the di-methylated form of human TET2 at arginine 1682, a post-translational modification linked to regulation of DNA methylation dynamics. TET2 is a 5-methylcytosine dioxygenase and a well-characterized tumor suppressor frequently mutated in hematological malignancies. The antibody is validated for immunofluorescence (IF) staining on human cells and tissue, allowing visualization of methylated TET2 in situ. Store at -20°C in small aliquots to minimize freeze-thaw cycles and preserve antibody integrity. Intended for research use only, the unconjugated format gives flexibility to pair with secondary antibodies and detection chemistries, including fluorophore-conjugated secondaries for multiplex imaging. The polyclonal nature of the reagent provides recognition of multiple epitopes around the methylated R1682 site, which can support robustness in samples where the target is expressed at low levels.