Anti-TESK2 Antibody

A rabbit-derived polyclonal IgG reagent from Antibodies.com targets Testis-Specific Kinase 2 (TESK2), a dual-specificity serine/threonine kinase that phosphorylates cofilin and contributes to actin cytoskeleton remodeling, integrin-mediated adhesion, and focal adhesion turnover in mammalian cells.

This unconjugated polyclonal preparation is supplied as 50 µl and is validated for western blot detection of endogenous TESK2 expression in mouse and rat tissue lysates. Researchers investigating spermatogenesis, neuronal development, or TESK2-linked pathways in cancer cell migration and invasion can probe whole-cell extracts or subcellular fractions on standard SDS-PAGE gels with chemiluminescent or colorimetric secondary detection.

Clonality is polyclonal with an IgG isotype, providing a broad response against multiple epitopes across the kinase domain and flanking regions of TESK2. Reactivity has been confirmed against mouse and rat orthologs, while cross-reactivity with other species has not been characterized. The unconjugated format allows pairing with any HRP-, biotin-, or fluorophore-conjugated secondary antibody matched to the experimental design, giving flexibility across blotting membranes, imaging workflows, and immunoprecipitation follow-up studies of kinase-substrate interactions.

Brief centrifugation before opening recovers the full 50 µl volume. Aliquot the reagent and store refrigerated to minimize freeze-thaw cycles and preserve antibody activity across repeated western blot experiments.