Anti-TERF2 Antibody

TERF2 (Telomeric Repeat-Binding Factor 2) is a core component of the shelterin complex that binds double-stranded telomeric DNA repeats and shields chromosome ends from being recognized as DNA double-strand breaks. The rabbit polyclonal Anti-TERF2 Antibody from Antibodies.com supports research on telomere maintenance, the DNA damage response, and shelterin complex composition in mammalian cells.

Validated for western blot and immunoprecipitation, the unconjugated IgG reagent is supplied as a 100 µL aliquot and cross-reacts with both human and mouse TERF2, enabling comparative work across cell lines and primary tissue lysates.

• Host: Rabbit; clonality: polyclonal; isotype: IgG
• Conjugate: unconjugated, ready for custom secondary antibody pairing
• Species reactivity: Human, Mouse
• Validated applications: western blot (WB) and immunoprecipitation (IP)
• Format: 100 µL vial

Beyond direct detection of endogenous TERF2 in whole-cell extracts, this antibody can be deployed for pull-down experiments and co-immunoprecipitation studies with other shelterin components such as TRF1, TIN2, RAP1, TPP1, and POT1. It is a useful reagent for laboratories investigating telomere length regulation, replicative senescence, alternative lengthening of telomeres (ALT), and the mechanisms that protect chromosomal ends from inappropriate repair.