Anti-TCP1 Antibody - Identical to Abcam (ab185687)

A polyclonal rabbit IgG reagent from Antibodies.com directed against TCP1 (T-complex protein 1 subunit alpha), the alpha subunit of the cytosolic group II chaperonin CCT/TRiC complex that mediates ATP-dependent folding of actin, tubulin, and other client substrates. Supplied as an unconjugated antibody in a 200 µl vial, the reagent is validated for western blotting (WB), immunohistochemistry (IHC), and immunofluorescence (IF), with reactivity confirmed against human, mouse, and rat samples. The epitope recognized matches that of the reference reagent ab185687, so existing protocols, imaging conditions, and dilutions developed for that antibody can be transferred directly without re-optimization. Researchers use this reagent to probe CCT subunit expression, map cytoplasmic localization in cultured cells, and investigate the cellular response to proteotoxic stress, supporting comparative chaperone biology across vertebrate model systems. For handling, aliquot upon arrival and store frozen; repeated freeze-thaw cycles should be avoided to preserve binding activity.