Anti-TCN1 Antibody

This polyclonal antibody from Antibodies.com targets TCN1 (Transcobalamin 1), a vitamin B12-binding glycoprotein also known as haptocorrin. TCN1 is synthesized primarily by salivary gland epithelial cells, gastric mucosa, and granulocytes, where it participates in the transport of cobalamin through body fluids and mucosal secretions. The reagent is raised in rabbit hosts and validated for western blot (WB) and immunofluorescence (IF) workflows, supporting studies of B12 metabolism, mucosal immunity, and granulocyte biology in human samples. Supplied as an unconjugated preparation in a 100 µL volume, the antibody is suited to immunoblotting whole-cell lysates and to visualizing TCN1 distribution in fixed cell or tissue sections. Researchers investigating haptocorrin expression across cancer cell lines or chronic myeloid disorders benefit from the polyclonal format, which recognizes multiple epitopes of the target protein and helps amplify signal from low-abundance samples.