Anti-TCF4 Antibody

TCF4 is a class I basic helix-loop-helix transcription factor, also known as E2-2 or ITF-2, that recognizes E-box motifs and drives gene expression programs in lymphoid and neural development. This polyclonal reagent from Antibodies.com is supplied as a 100 µl liquid aliquot at 1 mg/ml, formulated in PBS with 0.1% sodium azide and 50% glycerol for routine cold storage. It is validated for western blot analysis of endogenous TCF4 protein, immunohistochemistry on formalin-fixed tissue sections, and immunofluorescence staining of cultured mammalian cells. The antibody detects the human, mouse, and rat TCF4 orthologue, supporting comparative studies that span patient-derived samples and rodent model systems. Researchers working on Pitt-Hopkins syndrome, B-lymphocyte maturation, or cortical neurogenesis commonly use this reagent to confirm expression changes at the protein level.