Anti-TBRG1 Antibody

Raised in a rabbit host, this unconjugated IgG polyclonal antibody recognizes TBRG1 (Transforming Growth Factor Beta Regulator 1), a nuclear protein implicated in cell cycle arrest and the DNA damage response. The reagent is validated for Western blot analysis on human samples and is supplied as 200 µl of liquid in a single vial, ready for direct use in standard immunoblotting workflows.

TBRG1 functions as a growth inhibitor that interacts with MDM2 and ARF, placing it within the p53 tumor suppressor network, and altered expression has been reported in transformed cell lines. Researchers studying genomic stability, proliferation control, or NIAM-associated nuclear signaling can use this antibody to detect endogenous TBRG1 in whole-cell lysates separated by SDS-PAGE. Polyclonal reactivity provides broader epitope coverage than monoclonal alternatives, supporting detection of the protein under denaturing, reducing conditions.

Refrigerate on receipt and avoid repeated freeze-thaw cycles to preserve binding activity. Each lot is quality-controlled by Antibodies.com to help laboratories investigating DNA damage checkpoints, cell cycle regulation, and tumor biology obtain reproducible Western blot data.