Anti-TBPL1 Antibody

Primary antibody raised in rabbit against TBPL1, a TATA-box-binding protein-like transcription factor involved in RNA polymerase II-mediated transcription and germ cell development. This polyclonal reagent from Antibodies.com is supplied as a 100 µl vial of unconjugated antibody at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, suitable for storage at 4 °C short term and -20 °C long term. The antibody has been validated for western blot (WB) and immunohistochemistry (IHC) workflows, with reactivity confirmed against human, mouse, and rat samples, making it applicable to comparative studies across species. TBPL1, also referred to as TBP-like factor (TLF) or TBP-related factor 2 (TRF2), is expressed in testis and in embryonic stem cells, where it supports spermatogenesis and early differentiation programs. Researchers studying transcription factor networks, chromatin-associated complexes, or reproductive biology can use this reagent to detect endogenous TBPL1 protein levels, verify gene knockdown or knockout efficiency at the protein level, and characterize expression patterns across tissue sections and cell lysates.