Anti-TBP Antibody

This rabbit polyclonal IgG antibody from Antibodies.com targets human TATA-binding protein (TBP), the central subunit of the TFIID complex that recognizes TATA box elements and nucleates assembly of the RNA polymerase II pre-initiation complex. Supplied as an unconjugated reagent in a 100 µL volume, it is validated for western blot, immunohistochemistry, immunofluorescence, and flow cytometry on human samples. The antibody detects endogenous TBP in nuclear and whole-cell lysates, supporting research on basal transcription, transcription factor recruitment, chromatin-associated complexes, and promoter-proximal regulation. As a polyclonal reagent raised in rabbit, it binds multiple epitopes of TBP, which makes it well suited for chromatin immunoprecipitation-grade enrichments and co-staining experiments with RNA polymerase II subunits. Working aliquots should be prepared on receipt and stored refrigerated to limit freeze-thaw cycles; the antibody is intended for research use only.