Anti-TBLR1 Antibody

This unconjugated polyclonal antibody from Antibodies.com targets human TBLR1 (Transducin beta-like 1 X-linked receptor 1), a nuclear transcriptional regulator that functions as an exchange factor within the NCoR/SMRT corepressor complex and modulates Wnt/β-catenin signaling. Raised in rabbit and supplied as 100 µL of liquid reagent, the antibody is validated for western blot, immunohistochemistry, and immunofluorescence detection of the endogenous human protein.

TBLR1 is well characterized for recruiting the 19S proteasome to chromatin, a mechanism that removes transcriptional repressors from target promoters and is implicated in cancer biology, neurodevelopmental disorders, and stem cell maintenance. The polyclonal format provides recognition of multiple epitopes along the target, supporting robust signal across heterologous sample types. For long-term storage, aliquot the reagent and freeze at -20°C to -80°C, avoiding repeated freeze-thaw cycles that degrade antibody activity. Prepare working dilutions in blocking buffer immediately before use and consult the supplied documentation for recommended starting dilutions in each application.