Anti-TBLR1 Antibody

TBLR1 (Transducin Beta-Like 1 X-Linked Receptor 1) is a WD40-repeat core subunit of the NCoR and SMRT transcriptional corepressor complexes, and this unconjugated mouse monoclonal antibody from Antibodies.com provides a validated reagent for probing its expression and chromatin-associated functions. The clone is supplied as a purified immunoglobulin at 50 µL in 0.1 M Tris-Glycine buffer (pH 7.4) with 150 mM NaCl, 50% glycerol, and 0.2% sodium azide as preservative, and the glycerol-based formulation supports storage at -20 °C with aliquoting recommended on first use to limit repeated freeze-thaw exposure. Validated applications include Western blot, immunohistochemistry, and immunocytochemistry on human and mouse samples, and the unconjugated format offers flexibility for downstream secondary antibody pairing, custom labeling, or chromatin immunoprecipitation workflows. TBLR1 participates in nuclear receptor-mediated transcriptional repression and contributes to Wnt/β-catenin signaling, where it bridges repressor complexes to chromatin, making this Primary Antibody suitable for research into corepressor recruitment, gene regulation mechanisms, and signaling pathway crosstalk.