Anti-TBC1D15 Antibody

Antibodies.com supplies this anti-TBC1D15 antibody as a rabbit polyclonal IgG reagent raised against TBC1 domain family member 15, a Rab-GTPase-activating protein that controls Rab7 and Rab11 activity and participates in Parkin-mediated mitophagy through binding LC3/GABARAP family members on autophagosomal membranes. The unconjugated polyclonal preparation is provided as 200 µl in a single vial and is validated for Western blot detection of endogenous TBC1D15 in lysates from human, mouse, and rat sources.

The reagent supports research into mitochondrial quality control, endosomal sorting, and autophagosome maturation, where TBC1D15 coordinates turnover of damaged mitochondria. Because the antibody is unconjugated, it can be paired with HRP- or fluorophore-conjugated secondary reagents for chemiluminescent or fluorescent Western blot imaging. Aliquoting on receipt and storing the working stock at -20°C protects IgG activity and limits repeated freeze-thaw cycles, and the vial contents are intended for research use only.