Anti-Tau (phospho-T534) Antibody

This rabbit polyclonal antibody from Antibodies.com is raised against the microtubule-associated protein Tau phosphorylated at threonine 534 (p-T534), a post-translational modification studied in Alzheimer's disease and other tauopathies. The reagent is supplied as a 100 µl volume at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, ready to dilute directly into standard western blot workflows.

Reactive with human, mouse, and rat samples, the polyclonal reagent selectively recognises the phosphorylated T534 epitope, enabling researchers to monitor site-specific phosphorylation changes in cell and tissue lysates. The unconjugated format gives users flexibility to pair the antibody with HRP, fluorescent, or biotin secondary detection reagents depending on the experimental setup, without the constraints of a pre-conjugated reporter.

Intended for research use only, the antibody supports investigations of Tau hyperphosphorylation in neurodegeneration models, including studies of the kinases and phosphatases that act on the T534 residue and comparative analyses of phospho-site occupancy across disease and control tissue. Each vial is provided at a working concentration that supports both single-gel experiments and larger screening campaigns without immediate re-aliquoting, and the glycerol-based buffer helps preserve antibody activity through repeated freeze-thaw cycles on the bench.