Anti-Tau (phospho S422) Antibody

Rabbit polyclonal IgG antibody from Antibodies.com targets the phosphorylated serine 422 epitope of the microtubule-associated protein Tau, a post-translational modification linked to neurofibrillary tangle formation in Alzheimer's disease and other tauopathies. Raised in rabbit and supplied as an unconjugated reagent in a 50 µl vial, this primary antibody is validated for Western blot detection across human, mouse, and rat sample lysates, enabling researchers to probe disease-associated tau phosphorylation in cultured neurons, brain tissue homogenates, and relevant model systems. The polyclonal formulation provides broader epitope coverage around the S422 phospho-site, supporting studies of kinase signaling cascades, paired helical filament assembly, and pathology progression in neurodegenerative disease research. Storage at -20 °C in small aliquots is recommended to preserve phospho-specific binding activity across multiple freeze-thaw cycles.