Anti-Tau (phospho S356) Antibody

This polyclonal antibody from Antibodies.com is raised in rabbit and selectively recognizes the Tau protein phosphorylated at serine 356, a post-translational modification investigated in studies of Alzheimer's disease and other tauopathies. The unconjugated IgG reagent is supplied as a 100 µl vial and is validated for Western blot and immunofluorescence across human, mouse, and rat sample types. Because phospho-epitopes are labile, the reagent should be stored frozen in single-use aliquots to preserve activity through repeated freeze-thaw cycles. Staining of fixed cells and tissue sections alongside immunoblotting of brain and neuronal lysates lets researchers track the spatial distribution and abundance of this phosphorylated Tau species independently of total Tau levels. The antibody targets an epitope within the C-terminal projection domain, where phosphorylation modulates microtubule interactions and is implicated in neurofibrillary pathology. Each vial is intended for research use only and should be handled with standard laboratory precautions for protein reagents.