Anti-Tau (phospho S214) Antibody

This rabbit polyclonal IgG antibody from Antibodies.com targets Tau phosphorylated at serine 214, a post-translational modification linked to Alzheimer's disease pathology and other tauopathies. Raised in rabbit and supplied unconjugated, the reagent is validated for Western blot detection of phospho-S214 Tau in samples from human, mouse, and rat origins. Each vial contains 200 µl of polyclonal antiserum, supporting multiple immunoblotting experiments. The antibody recognizes a phosphorylated epitope and serves researchers investigating tau hyperphosphorylation, microtubule-associated protein dysfunction, and neurodegenerative disease mechanisms. Common applications include studies of paired helical filament formation, neurofibrillary tangle pathology, and kinase signaling pathways that modify Tau, including GSK-3β and PKA. The unconjugated format offers flexibility in choosing secondary antibodies and detection chemistries tailored to specific experimental workflows.