Anti-Tau (phospho S214) Antibody

Phosphorylation of the microtubule-associated protein Tau (MAPT) at serine 214 is one of several post-translational modifications studied in the context of neuronal cytoskeleton regulation and tauopathies. This unconjugated IgG polyclonal reagent from Antibodies.com is raised in rabbit and selectively detects Tau only when the S214 site is phosphorylated, allowing researchers to monitor this specific phospho-epitope by Western blot across human, mouse, and rat samples.

Provided as a 100 µL vial of liquid antibody without a conjugated reporter, the reagent is paired with secondary detection systems chosen by the user, supporting chemiluminescent or fluorescent Western blot workflows depending on laboratory preference. The reagent is intended for research use only and has been validated for Western blot application on lysates derived from the listed reactive species.

Recommended handling includes brief storage under refrigerated conditions for active use, with longer-term aliquoting and freezing to preserve activity across multiple experiments. Researchers studying Alzheimer's disease, frontotemporal dementia, and related neurodegenerative models commonly employ phospho-S214 Tau antibodies to profile kinase activity, cellular stress responses, and pathological tau accumulation in cell and tissue lysates.