Anti-Tau (K225) Antibody

Produced by Antibodies.com, this unconjugated rabbit polyclonal antibody recognizes the microtubule-associated protein Tau at an epitope centered on lysine 225 (K225), a residue located within the proline-rich region of the protein. The reagent is intended for researchers investigating Tau biology in the context of neurodegenerative disease, including Alzheimer's disease, frontotemporal dementia, and other tauopathies where site-specific characterization of Tau is a focus of investigation.

Supplied as 100 µl of a 1 mg/ml stock in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2, the antibody is validated for Western blot and cross-reacts with Human, Mouse, and Rat samples, supporting cross-species studies in neuroscience and tauopathy modeling. The vial should be refrigerated after receipt; aliquoting is recommended to limit freeze-thaw exposure of the stock, and the included sodium azide serves as a preservative against microbial contamination.

Investigators studying Tau phosphorylation, post-translational modification more broadly, microtubule binding, and protein aggregation in tauopathies can use this reagent to probe site-specific features of Tau, compare Tau species across experimental conditions, and characterize disease-associated Tau variants in cell and tissue models.